Si ya no deseamos tener la aplicación corriendo en nuestro Ubuntu.

sudo apt-get remove wine
rm -rf $HOME/.wine
rm -f $HOME/.config/menus/applications-merged/wine*
rm -rf $HOME/.local/share/applications/wine
rm -f $HOME/.local/share/desktop-directories/wine*
rm -f $HOME/.local/share/icons/????_*.xpm

Y luego:

sudo apt-get remove –purge wine

sudo apt-get update
sudo apt-get autoclean
sudo apt-get clean
sudo apt-get autoremove